Ownership

Top Holders

Holder Shares Held % O/S Share Change Filing Date
BlackRock Institutional Trust Company, N.A. 2,723,068 12.02 334,167 3/31/19
Fidelity Management & Research Company 1,589,734 7.02 1,489,484 3/31/19
Redmile Group, LLC 1,222,405 5.40 131,010 3/31/19
OrbiMed Advisors, LLC 1,181,214 5.22 81,214 3/31/19
The Vanguard Group, Inc. 1,143,850 5.05 102,816 3/31/19
Victory Capital Management Inc. 1,001,990 4.42 214,475 3/31/19
Emerald Advisers LLC 726,122 3.21 443,776 3/31/19
Dimensional Fund Advisors, L.P. 722,459 3.19 -4,835 3/31/19
Lord, Abbett & Co. LLC 708,072 3.13 635,907 3/31/19
Gilder Gagnon Howe & Co. LLC 553,298 2.44 72,093 3/31/19

* Insider values reflect direct beneficial ownership.

Copyright Thomson Reuters Corporation